The dosage of D-dimer is an aid in the diagnosis of venous thrombosis formed, phlebitis as pulmonary embolism.

This examination is also useful when in doubt about a diagnosis of disseminated intravascular coagulation.


Degradation product of fibrin, D-dimer in the plasma appears in a non-physiological activation of coagulation.


5 mL sample of blood sodium citrate; it can be done on the tube used for the construction and measuring fibrinogen.

the dosage is through fast, slide, or longer, ELISA.


Whatever the reagents used, the rate is, in any case, normally less than 500 mcg / L.

A higher rate is observed:

– If formed venous thrombosis, hematoma or cancer;

– During the thrombolytic therapy.

Normal levels of D-dimer eliminates the diagnosis of venous thrombosis and pulmonary embolism if the analysis was performed by ELISA, spreading blade being on him, insensitive.



Practical advice:

After air travel lasting more than 4 hours in any discomfort, any pathology nonexistent until then, we should mention venous thrombosis or pulmonary embolism, and request a determination of D-dimer.

However, postoperative, the review has no diagnostic value.

Prevention is key: during a trip extended plane, advisor to small movements of the feet (extension, flexion), wearing stockings, drinking lots to prevent thrombosis.


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