D-dimer

 

Indications:

The dosage of D-dimer is an aid in the diagnosis of venous thrombosis formed, phlebitis as pulmonary embolism.

This examination is also useful when in doubt about a diagnosis of disseminated intravascular coagulation.

Principle:

Degradation product of fibrin, D-dimer in the plasma appears in a non-physiological activation of coagulation.

D-dimerTechnique:

5 mL sample of blood sodium citrate; it can be done on the tube used for the construction and measuring fibrinogen.

the dosage is through fast, slide, or longer, ELISA.

Results:

Whatever the reagents used, the rate is, in any case, normally less than 500 mcg / L.

A higher rate is observed:

– If formed venous thrombosis, hematoma or cancer;

– During the thrombolytic therapy.

Normal levels of D-dimer eliminates the diagnosis of venous thrombosis and pulmonary embolism if the analysis was performed by ELISA, spreading blade being on him, insensitive.

Cost:

B30.

Practical advice:

After air travel lasting more than 4 hours in any discomfort, any pathology nonexistent until then, we should mention venous thrombosis or pulmonary embolism, and request a determination of D-dimer.

However, postoperative, the review has no diagnostic value.

Prevention is key: during a trip extended plane, advisor to small movements of the feet (extension, flexion), wearing stockings, drinking lots to prevent thrombosis.

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