ROLES: Antioxidant role by activating selenium glutathione peroxidases (4 types of GPX Detoxifies hydrogen peroxide (H202- hydrogen peroxide) into water in plasma and cells thanks to the GPX1 enzyme Anti NFKappaB factor: selenium contributes with all antioxidants and polyphenols to modulate inflammatory responses Detoxification: Blocks heavy metals: lead, mercury, cadmium and allows their urinary elimination