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Drugs During Pregnancy




* Aminoglycosides: can be used for periods of less than a week for serious infection

* NSAIDs: to be used in case of severe birth threat before 32 weeks.

If NSAIDs are used after -> risk of IRA; risk of premature closure of the ductus arteriosus => PAH.

* Antibiotics:

– Beta-lactams pass the placenta but did not cause problems

– Macrolides do not pass the placenta

– The sulfonamides are cons-indicated except in cases of fetal toxoplas-mose

* Beta-blockers: cross the placenta; they are responsible in the new-born to a Rating Decrease FC and a risk of hypoglycemia

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