Tag: INR

  • Prothrombin Time and INR (International Normalized Ratio)

    Prothrombin Time and INR (International Normalized Ratio)

    Indications: Used to be a bleeding disorder, whether congenital or acquired, examination serves primarily to monitor patients on oral anticoagulant treatment based on anticoagulants. These drugs lower blood clotting by decreasing the synthesis of factors II, VII, IX and X coagulation. This assay is also used to assess liver function in case of failure as…

  • Anticoagulant Therapy

    Anticoagulant Therapy

    Warning: • Any heparin requires a platelet count check twice a week. • Early relay by vitamin K antagonists (VKA) reduces the risk of thrombocytopenia. • Thrombocytopenia heparin must be confirmed in vitro (Immuno-Allergy-indicating definitely against heparin, except in exceptional situations). • Monitoring of VKA based on the assessment of the International Normalized Ratio (INR)…

  • Vitamin K antagonist

    Vitamin K antagonist

    – The VKA act through competitive inhibition of hepatic synthesis of certain clotting factors vitamin K-dependent: prothrombin (II); proconvertin (VII); factor IX; Factor X (X). – Protein C and Protein S (coagulation inhibitors) are also vitaminic-K-dependent. – Two families derivatives indandione (fluindione or Previscan) and coumarin (acenocoumarol or Sintrom®; warfarin or Coumadin®). – Fixing to…