Tag: Warfarin

  • Vitamin K antagonist

    Vitamin K antagonist

    – The VKA act through competitive inhibition of hepatic synthesis of certain clotting factors vitamin K-dependent: prothrombin (II); proconvertin (VII); factor IX; Factor X (X). – Protein C and Protein S (coagulation inhibitors) are also vitaminic-K-dependent. – Two families derivatives indandione (fluindione or Previscan) and coumarin (acenocoumarol or Sintrom®; warfarin or Coumadin®). – Fixing to…