Tag: Antithrombin

– Heparins are indirect thrombin inhibitors (IIa), acting by means of a plasma cofactor antithrombin III (AT III). The action of heparin-AT III complex is directed against thrombin (IIa) and against factor Xa (Stuart factor). – This mode of action explains the inefficiency of heparin in patients with congenital or acquired deficiency in AT III.…