The test is useful in diagnosing tumors of the adrenal pheochromocytoma kind.
The Secret medulla adrenaline and noradrenaline. Both catecholamines are measurable in the urine.
Urine collection for 24 hours hydrochloric acid, stored at 4 ° C, protected from light. For example, for a collection of 8 pm to 8 am the next day to the patient urinate at 8 am, throwing urine and keep all the urine overnight 8am.
Dosing is by high performance liquid chromatography.
Normally, urinary catecholamines levels below 100 micrograms / 24 hours or 0.6 mmol / 24 h, distributed as follows:
– Noradrenaline: concentration <80 mg / 24 h;
– Adrenaline concentration <20 mg / 24 h.
Each laboratory has its standards, however.
A greater than 139 mcg rate is the best sign of pheochromocytoma.
As part of treatment monitoring, metering allows its effectiveness.
Before the irregularity of the tumor secretion, it is often useful to repeat the examination for three consecutive days.