Medical Actu – Actualités Médicales Quotidienne – Actualité Santé

Tag: Antibodies

  • Antithyroid Antibodies

    Antithyroid Antibodies

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    Dr. Taoufik
    in

    Indications: if the review is essentially practical suspected thyroid autoimmune diseases (such as Hashimoto thyroiditis, for example), but When it evoked the diagnosis of neonatal hyperthyroidism. Apart from the diagnostic indication, the examination will follow, during treatment or stage of pregnancy, treated hyperthyroidism Graves. Principle: The antibodies are directed essentially against thyroglobulin, microsomes and the…

  • Anti-Sperm Antibodies

    Anti-Sperm Antibodies

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    by

    Dr. Taoufik
    in

    Indications: The examination allows to find an immunological cause infertility: the presence of iso-antibodies in women and autoantibodies in humans. Principle: The antibodies cause infertility with sperm agglutination. Technique: In humans: taking 5 mL of blood in a dry tube and seminal fluid. For women: 5 mL sample of blood and mucus. The agglutination of…

  • Gliadin Antibodies

    Gliadin Antibodies

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    by

    Dr. Taoufik
    in

    Indications: The dosage of anti-gliadin antibodies provides help diagnose celiac disease (gluten intolerance) in children. Principle: A blood test can detect the presence of blood antibodies against gliadin component of the immune response in celiac disease. These antibodies disappear when gluten free diet. Technique: Blood sample to detect IgA and IgG: – IgA are found…

  • Anti-dsDNA Antibodies. Farr Assay

    Anti-dsDNA Antibodies. Farr Assay

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    by

    Dr. Taoufik
    in

    Indications: The presence of anti-dsDNA antibodies is observed that in case of lupus. In contrast, anti-DNA antibodies denatured, less specific, are found in several autoimmune diseases, including rheumatoid arthritis, scleroderma and also hepatitis. Principle: The Farr assay consists in bringing the patient’s serum with the DNA labeled with carbon 14. It then precipitated proteins by…

  • Nuclear antibodies (ANA)

    Nuclear antibodies (ANA)

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    Dr. Taoufik

    Antinuclear antibodies (ANA), also known as ANA (antinuclear antibodies for) or antinuclear antibodies (FAN) are autoantibodies recognizing antigens present in nuclei. They appear in the serum of patients with connective (or collagen). Indications: • Finding a systemic lupus erythematosus (SLE) in front of a photosensitivity, a vespertilio, a non-erosive arthritis, proteinuria, pleurisy, hemolytic anemia. •…

  • Anti-neutrophil Cytoplasmic Antibodies (ANCA)

    Anti-neutrophil Cytoplasmic Antibodies (ANCA)

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    Dr. Taoufik

    The anti-neutrophil cytoplasmic antibody called ANCA (anti-neutrophil cytoplasmic for antibodies) are autoantibodies recognizing antigens neutrophil cytoplasmic. They are found in systemic vasculitis, particularly in Wegener’s granulomatosis or Wegener’s granulomatosis (WG). They are of two types: • inducing ANCA by indirect immunofluorescence (IIF), a diffuse cytoplasmic staining (c-ANCA); • perinuclear ANCA fluorescence (p-ANCA). Indications: Finding a…

  • Nuclear antigens antibodies or soluble anti-ENA antibodies Antibodies antihistones

    Nuclear antigens antibodies or soluble anti-ENA antibodies Antibodies antihistones

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    by

    Dr. Taoufik

    Antibodies against the soluble nuclear antigen, also called ENA (for extractable nuclear antigen) antibody or antiextraits thymus cells (anti-ECT) recognize soluble compounds of the nucleus. Only a small number of them are sought routinely. Indications: Balance sheet of connective. Sample: Venous blood clotted. Typical values: These antibodies are not present in normal subjects. Interpretation: Anti-ENA…

  • Anti-native DNA antibody (anti-DNA Ab)

    Anti-native DNA antibody (anti-DNA Ab)

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    by

    Dr. Taoufik

    The anti-dsDNA autoantibodies (dsDNA) (or double-stranded DNA) are found frequently in systemic lupus erythematosus (SLE). Their research contributes to the diagnosis and monitoring of disease. Indications: Research and monitoring of a suspected LEAD on erythema “butterfly wing”, photosensitivity, chronic non-erosive arthritis, pleurisy, pericarditis, proteinuria, hemolytic anemia. Sample: Venous blood clotted. Typical values: Sensitivity Thresholds are…